NFL · Indianapolis Colts · 08:37 ET · via @RapSheet

NFL Injury Report Looks Like a Pro Bowl Roster: Nacua, Flowers, and Collins Could All Sit

Editorial sports image for NFL Injury Report Looks Like a Pro Bowl Roster: Nacua, Flowers, and Collins Could All Sit

Ian Rapoport via SportsCenter: 'Injury updates on Puka Nacua, Zay Flowers, and Nico Collins, all of whom may miss Sunday.'

The NFL's wide receiver injury report is starting to look like a Pro Bowl roster. Ian Rapoport just dropped a bomb via SportsCenter that , , and Nico Collins could all be in street clothes this Sunday.

If you are holding fantasy shares or looking at weekend totals, it is time to hit the panic button. Losing one top target is a headache, but losing three of the most electric pass-catchers in the league on the same weekend is a full-blown crisis for anyone trying to evaluate these offenses.

is dealing with a hamstring issue that kept him out of practice all week. The are heading into a massive showdown against the , and right now Baltimore is sitting as a 3.5-point favorite with a total of 53. Trying to hit that over without 's top perimeter weapon feels like trying to start a fire with wet cardboard.

Down in , Nico Collins is also fighting a hamstring strain. He has not practiced, and the Houston are staring down a divisional clash with the . Collins already missed time, and his absence turns 's passing attack from a lethal weapon into a highly predictable check-down operation.

Then there is . The are gearing up to play the , and missing Nacua means is going to be throwing to guys who were probably asking for directions to the stadium last month.

This is the reality of the modern NFL. You build a high-flying offense around elite separators, and the second a hamstring tweaks, the entire game plan goes out the window. The betting markets are going to be scrambling to adjust these lines, because the drop-off from these three stars to their backups is roughly the distance from the penthouse to the pavement.

Keep an eye on the final inactive lists Sunday morning. If all three officially sit, expect a heavy dose of the run game and a lot of frustrated fans staring blankly at their screens by the early afternoon window.